Increasingly, format flexibility is becoming a requirement to address patient issues such as swallowing. The FDA also continues to push for pediatric-friendly formulations. Taste, smell, and mouth feel are the key product features to address when developing pediatric formulations. And Incremental formulation and clinical research costs require cost-effective solutions with flexibility in manufacturing scale. These drivers are why customers continue to come back to Adare Pharma Solutions for their taste-masking challenges.

Among various taste masking strategies, physical barrier is one of the most efficient technologies, and Adare offers industrially feasible physical barrier technologies, such as Microcaps®  and Optimµm®, for taste masking and dosage forms for pediatric populations.

Microencapsulation by coacervation:

As the world leader in coacervation, Adare’s Microcaps® technology is widely scene as the industry leading taste-masking solution with a wide variety of delivery formats.

Uniform coating of a solid particle or liquid droplet with a rigid semi-permeable polymer Creates a physical barrier: Effective taste masking Customized release profile Turn liquids into powders Combine incompatible APIs Final dosage forms: Powder Dry syrup Orally disintegrating tablets Parvulet® dosage form: food-like texture

Core In the manufacturing vehicle Deposition of Gel-like coating Completed Capsules

Proprietary Taste-Masking Process Although spherical particles are shown (yellow), the Microcaps® coacervation process can also be used for varying non-isometric particle shapes. Our Process Also Offers: Small Particle Size – down to 150-200 µm Highly efficient coating – usually 10-20% Tunable and reproducible dissolution profile Short processing time – one shift Processing time not impacted by coating amount High manufacturing capacity Can manage different particle shapes