Sustained release profiles and targeted delivery of pharmaceutical products
A matrix tablet is coated with functional polymers, followed by a blend of hydrophilic and hydrophobic polymers. Layered erosion and diffusion of the drug matrix tablet result in a controllable release. An effective solution for targeted drug delivery through customized and sustained release technology. Assists development of high-dosage and sustained release products for once-daily administration.
Customized release profiles, including zero-order release
This technology incorporates a blend of hydrophilic polymers that control drug release via diffusion through, and erosion of, a matrix tablet. Some layers contain drug substance; others are rate controlling polymers.
Key Benefits
- Matrix tablet utilizes a combination of water soluble particles and active drug
- Suitable for high drug loading
- Supports sustained release, once a day dosing
Speak With An Expert
Nathan Dormer
Director, Drug Product Development
Nathan Dormer, Ph.D., is the Senior Director of Drug Product Development & Site Leader at Adare Pharma Solutions and is responsible for pharmaceutical development activities at Adare’s facilities, supporting a team of formulation scientists and analysts. He is a pharmaceutical scientist and bioengineer by training, with more than 16 years of experience developing microsphere-based solid oral and parenteral/implantable dosage forms in academic, innovator, and CDMO settings. Dr. Dormer earned his B.S. in Chemical Engineering and his Ph.D. (w/Honors) in Bioengineering from The University of Kansas while receiving NIH-sponsored Pharmaceutical Biotech Training.