Adaptdose^™, Adare’s unique commercialized approach to adaptive formulation design, provides the ability to combine multiple active ingredients and/or delivery rates in a single capsule. Adaptdose^™ is also appropriate for dose escalation studies.

Adare’s Adaptdose^™ technology platform provides a tool that can eliminate the need to reformulate after Phase I and overcomes several technical hurdles in the development and scale up of (1) new molecules, (2) binary and tertiary mixtures of active ingredients, zero and first order drug release matrices, or (3) scalable clinical trial materials used in dose ranging or adaptive dose clinical studies. Adaptdose^™ technology allows us to incorporate granules, beadlets / pellets, and mini-tablets into a single capsule without the step of mixing the different materials prior to filling using our commercially engineered, accurate and high speed equipment (capable of fill speeds over 100,000 units per hour).

Adaptdose^™ can serve as a unique, commercial ready technology that allows our clients to quickly create custom oral delivery systems, thereby reducing the time to market, improving the flexibility of system modifications during clinical studies, and decreasing the potential to reformulate the product. It is a platform that can also help companies to bring new Fixed Dose Combinations to clinical research and commercial quickly.