Duragran allows for more uniformity and precise control of targeted particle sizes while providing production time and cost savings

The Duragran patented process eliminates the need for extrusion and spheronization for high API-loaded drug particulates by using our fluid bed processing technology that combines the particle sizing and coating processes to create controlled-release beads/granules of uniform and narrow particle size range or the need to layer product onto a uniform sized sugar bead.

Duragran allows us to create controlled release beadlets/granules of uniform and narrow particle size range without the use of spheronization/extrusion equipment or the need to layer product onto a uniform sized sugar bead.

Duragran for more uniformity and targeted sizing

Duragran™ creates granules of more uniform particle size with easily modified process parameters that can be used to target a desired particle size that standard wet granulation processes cannot attain. The technology can be applied to controlled-release formulations and to create taste-masked, orally disintegrating tablet formulations.

 

Duragran provides many benefits by reducing:

  • Overall production costs
  • Energy requirements
  • Quality Unit in-process monitoring

Speak With An Expert

Profile Photo: Nathan Dormer

Nathan Dormer

Director, Drug Product Development

Nathan Dormer, Ph.D., is the Director of Drug Product Development at Adare Pharma Solutions and is responsible for pharmaceutical development activities at Adare’s Lenexa, KS and Philadelphia, PA facilities, where he supports a team of formulation scientists and analysts. He is a pharmaceutical scientist and bioengineer by training, with more than 16 years of experience developing microsphere-based solid oral and parenteral/implantable dosage forms in academic, innovator, and CDMO settings. Dr. Dormer earned his B.S. in Chemical Engineering and his Ph.D. (w/Honors) in Bioengineering from The University of Kansas while receiving NIH-sponsored Pharmaceutical Biotech Training.

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