Sustained release profiles and targeted delivery of pharmaceutical products
A matrix tablet is coated with functional polymers, followed by a blend of hydrophilic and hydrophobic polymers. Layered erosion and diffusion of the drug matrix tablet result in a controllable release. An effective solution for targeted drug delivery through customized and sustained release technology. Assists development of high-dosage and sustained release products for once-daily administration.
Customized release profiles, including zero-order release
This technology incorporates a blend of hydrophilic polymers that control drug release via diffusion through, and erosion of, a matrix tablet. Some layers contain drug substance; others are rate controlling polymers.
Key Benefits
- Matrix tablet utilizes a combination of water soluble particles and active drug
- Suitable for high drug loading
- Supports sustained release, once a day dosing
Speak With An Expert
Nathan Dormer
Director, Drug Product Development
Nathan Dormer, Ph.D., is the Director of Drug Product Development at Adare Pharma Solutions and is responsible for pharmaceutical development activities at Adare’s Lenexa, KS and Philadelphia, PA facilities, where he supports a team of formulation scientists and analysts. He is a pharmaceutical scientist and bioengineer by training, with more than 16 years of experience developing microsphere-based solid oral and parenteral/implantable dosage forms in academic, innovator, and CDMO settings. Dr. Dormer earned his B.S. in Chemical Engineering and his Ph.D. (w/Honors) in Bioengineering from The University of Kansas while receiving NIH-sponsored Pharmaceutical Biotech Training.